Publications

Welcome to our Publications Page, a dedicated space where we share a collection of our scientific peer-reviewed publications. 

Here, you will find a comprehensive array of research that reflects our therapy areas, commitment to advancing knowledge and innovation. 

We aim to make these valuable resources accessible to researchers, students, and inquisitive minds alike, fostering a community driven by curiosity and discovery. 

Explore, engage, and join us in our journey toward a brighter, more informed future.

Title Date Publication title Category Link to publications
Crystal structure and biophysical characterization of IspD from Burkholderia thailandensis and Mycobacterium paratuberculosis Acta Crystallographica Section F R&D/Discovery
Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation International Journal of Pharmaceutics R&D/Discovery
Toxicologic Pathology Forum Opinion Piece: Use of Virtual Control Groups in Nonclinical Toxicity Studies: The Anatomic Pathology Perspective Toxicologic Pathology R&D/Discovery
The Renovation of Good Clinical Practice: A Framework for Key Components of ICH E8 Therapeutic Innovation & Regulatory Science R&D/Discovery
Healthcare resource utilization, costs and treatment associated with myasthenia gravis exacerbations among patients with myasthenia gravis in the USA: a retrospective analysis of claims data Journal of Comparative Effectiveness Research Neurology
Estimating the economic burden of osteoporotic fractures in a multinational study: A real-world data perspective Osteoporosis International Bone
Towards in vitro models for reducing or replacing the use of animals in drug testing Nature Biomedical Engineering R&D/Discovery
Predicting seizure recurrence after an initial seizure-like episode from routine clinical notes using large language models: A retrospective cohort study The Lancet Digital Health Neurology
CD1a promotes systemic manifestations of skin disease Nature Communications Dermatology
The Lived Experiences of People with Progressive Supranuclear Palsy and Their Caregivers Neurology and Therapy Neurology
Contribution of the Dynamic Intestinal Absorption Model (Diamod) to the Development of a Patient-Centric Drug Formulation Molecular Pharmaceutics R&D/Discovery
SIGNET: Transcriptome-wide causal inference for gene regulatory networks Scientific Reports R&D/Discovery
Integrated proteomics and genomics analysis of paradoxical eczema in psoriasis patients treated with biologics Journal of Allergy and Clinical Immunology Dermatology
Validation of model-based design of experiments for continuous wet granulation and drying International Journal of Pharmaceutics R&D/Discovery
Bayesian Self-Optimization for Telescoped Continuous Flow Synthesis Angewandte Chemie R&D/Discovery
Long-term physical and psychiatric morbidities and mortality of untreated, deferred, and immediately treated epilepsy Epilepsia Neurology
Predicting crystal form stability under real-world conditions Nature R&D/Discovery
Epidemiology of focal onset seizures in children aged >1 month to 4 years in Europe, United States, and Canada: A literature review Seizure Neurology
Dynamic Regulatory Assessment: Unpacking the Process Reveals Readiness to Pilot for Europe-An EFPIA View Clinical Therapeutics R&D/Discovery
Mechanistic modeling of semicontinuous fluidized bed drying of pharmaceutical granules by incorporating single particle and bulk drying kinetics International Journal of Pharmaceutics R&D/Discovery