Neupro® (Restless Legs Syndrome) Europe In Europe, Neupro® (rotigotine transdermal patch) is indicated for the symptomatic treatment of moderate to severe idiopathic Restless Legs Syndrome in adults. USA In the US, Neupro® (Rotigotine Transdermal System) is indicated for the treatment of moderate-to-severe primary Restless Legs Syndrome. Prescribing information Europe SmPC Neupro® (EU) (Sourced from www.ema.europa.eu) Prescribing information USA US prescribing information Neupro®