Publications

Welcome to our Publications Page, a dedicated space where we share a collection of our scientific peer-reviewed publications. 

Here, you will find a comprehensive array of research that reflects our therapy areas, commitment to advancing knowledge and innovation. 

We aim to make these valuable resources accessible to researchers, students, and inquisitive minds alike, fostering a community driven by curiosity and discovery. 

Explore, engage, and join us in our journey toward a brighter, more informed future.

Title Date Publication title Category Link to publications

Crystal structure and biophysical characterization of IspD from Burkholderia thailandensis and Mycobacterium paratuberculosis

 Acta Crystallographica Section F R&D/Discovery

Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation

 International Journal of Pharmaceutics R&D/Discovery

Toxicologic Pathology Forum Opinion Piece: Use of Virtual Control Groups in Nonclinical Toxicity Studies: The Anatomic Pathology Perspective

 Toxicologic Pathology R&D/Discovery

Sustained effort network for treatment of status epilepticus/European academy of neurology registry on adult refractory status epilepticus (SENSE-II/AROUSE)

 BMC Neurology Epilepsy

ΔFosB is part of a homeostatic mechanism that protects the epileptic brain from further deterioration

 Frontiers in Molecular Neuroscience Neurology

Myeloid and lymphoid expression of C9orf72 regulates IL-17A signaling in mice

 Science Translational Medicine Immunology

The Renovation of Good Clinical Practice: A Framework for Key Components of ICH E8

 Therapeutic Innovation & Regulatory Science R&D/Discovery

Predicting seizure recurrence after an initial seizure-like episode from routine clinical notes using large language models: A retrospective cohort study

 The Lancet Digital Health Neurology

Towards in vitro models for reducing or replacing the use of animals in drug testing

 Nature Biomedical Engineering R&D/Discovery

Estimating the economic burden of osteoporotic fractures in a multinational study: A real-world data perspective

 Osteoporosis International Bone

Healthcare resource utilization, costs and treatment associated with myasthenia gravis exacerbations among patients with myasthenia gravis in the USA: a retrospective analysis of claims data

 Journal of Comparative Effectiveness Research Neurology

CD1a promotes systemic manifestations of skin disease

 Nature Communications Dermatology

Visualization Approach to Planning Benefit-Risk Assessments

 Therapeutic Innovation & Regulatory Science R&D/Discovery

The Lived Experiences of People with Progressive Supranuclear Palsy and Their Caregivers

 Neurology and Therapy Neurology

Contribution of the Dynamic Intestinal Absorption Model (Diamod) to the Development of a Patient-Centric Drug Formulation

 Molecular Pharmaceutics R&D/Discovery

SIGNET: Transcriptome-wide causal inference for gene regulatory networks

 Scientific Reports R&D/Discovery

Integrated proteomics and genomics analysis of paradoxical eczema in psoriasis patients treated with biologics

 Journal of Allergy and Clinical Immunology Dermatology

Validation of model-based design of experiments for continuous wet granulation and drying

 International Journal of Pharmaceutics R&D/Discovery

Bayesian Self-Optimization for Telescoped Continuous Flow Synthesis

 Angewandte Chemie R&D/Discovery

Dynamic Regulatory Assessment: Unpacking the Process Reveals Readiness to Pilot for Europe-An EFPIA View

 Clinical Therapeutics R&D/Discovery