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Since 2015, UCB has embarked on a very important change journey:
the Patient Value Strategy
In 2019 we entered the next phase of our Patient Value Strategy:
“Accelerate & Expand” (2019-2022)
During this phase, we are accelerating our growth potential by further improving our ability to demonstrate differentiation of our medicines, by accelerating our development timelines through new approaches and by improving patients’ access to our key medicines.
The evolving COVID-19 pandemic is profoundly impacting our lives, and places tremendous strain on healthcare systems and society at large. Since the start of the crisis, UCB has taken measures to protect our colleagues around the world, to stand by patients, to help our communities and take our part in the global response to the pandemic. We know that it is our responsibility to help where we can make an impact. Find out what actions UCB has taken here.
"Accelerate & Expand" (2019-2021)
Making significant progress towards this ambitious goal...
5 core products
2 recent launches
5 Phase late stage assets
bimekizumab
zilucoplan
rozanolixizumab
dapirolizumab pegol
Staccato® alprazolam
3 major acquisitions & many partnerships
2019 achievements
- Evenity® (romosozumab) and Nayzilam® (midazolam) were approved and launched as planned.
- bimekizumab delivered three positive Phase 3 study results in psoriasis; submission to regulatory bodies should occur mid-2020.
- UCB started multiple Phase 3 studies: bimekizumab in psoriatic arthritis, axial spondyloarthitis and hidradenitis suppurativa (early 2020), padsevonil in drug resistant epilepsy and rozanolixizumab in generalized myasthenia gravis as well as in immune thrombocytopenia.
- UCB0107, our anti-Tau antibody, reported positive Phase 1 results and will enter the confirmatory study.
2020 achievements
- Cimzia® available to Japanese patients living with plaque psoriasis, psoriatic arthritis, pustular psoriasis and psoriatic erythroderma
- Broadening the patient population for Vimpat® with approvals in the U.S., Europe and Japan as adjunctive therapy in the treatment of primary generalized tonic-clonic seizures (PGTCS)
- Promising progress for bimekizumab:
Phase 3b study BE RADIANT, comparing bimekizumab to secukinumab for the treatment of adults with moderate-to-severe plaque psoriasis met its primary end points.
Filing in the U.S. & EU for the treatment of adults with moderate-to-severe plaque psoriasis
- Acquisition of Ra Pharma, Engage Therapeutics & Handl Therapeutics
- Partnerships signed with Ferring Pharmaceuticals, Roche / Genentech, Lacerta Therapeutics, Microsoft
Our key medicines
We bring solutions to people living with neurological or immunological diseases.
Serving patients, our key medicines continued their growth in 2019.
Peak sales guidance
- Cimzia® > € 2 billion by 2024
- Vimpat® > € 1.5 billion by 2022
- Briviact® > € 600 million by 2026
Our pipeline
In a challenging environment, our pipeline builds the basis of UCB’s sustainable long term growth.
We continued to create value for patients, advancing our pipeline of potential solutions for severe diseases, expanding our capabilities by investing in state-of-the-art scientific platforms and medical advances, and further progress on our digital business transformation journey.
5 late stage assets
- Bimekizumab in psoriasis (PsO), psoriatic arthritis (PsA), axial spondyloarthritis (AxSpA) and hidradenitis suppurativa (HS)
- Zilucoplan in general Myasthenia Gravis (gMG)
- Rozanolixizumab in Immune ThrombocytoPenia (ITP) & Myasthenia Gravis (MG)
- Dapirolizumab pegol in systemic lupus erythematosus (SLE) in partnership with Biogen
- Staccato® alprazolam in acute epileptic seizure
Clinical studies index
UCB is committed to sharing information on studies and making study results publicly accessible. You will find below links to the clinical studies (Phase 2-4) of our main R&D projects.
More information about our clinical studies index and our position paper are available here.
February 2021
IMNM: Immune-Mediated Necrotizing Myopathy
* In partnership with Biogen
Zilucoplan is also being assessed in:
- COVID-associated ARDS by University of Ghent (Belgium), Medical Research Council (U.K.) & COMMUNITY Trial (U.S.)
- amyotrophic lateral sclerosis (ALS) by HEALEY ALS Platform Trial