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Osteoporosis is a disease of the bones in which the quality and density of bone is reduced 1. This makes bones porous and fragile, greatly increasing the risk of a fracture.
The loss of bone occurs quietly and progressively. A bone mineral density (BMD) test, most commonly performed with low radiation using dual-energy X-ray absorptiometry (DXA), is used, along with medical history, physical examination and laboratory tests to assess for osteoporosis and fracture risk.
Sometimes the first sign of osteoporosis is a fractured bone. Spinal vertebrae, the hip, and wrist are the most commonly affected bones, causing pain, immobility and, in some cases, hospitalisation.
The profound impact osteoporosis can have on quality of life is what inspires UCB to seek solutions in science.