Protein Kinase Inhibitor Chart

The Protein Kinase Inhibitor Chart is a snapshot of small molecule oral kinase inhibitors in clinical development collated by scientists at UCB. Here at UCB we wanted to make the data available to the scientific community enabling scientists to have a quick overview and summary of the field of protein kinase inhibitors. We have grouped the compounds by the primary protein target and where available given other significant targets of interest. Furthermore, the compounds are annotated with the experimental or predicted structural binding modes showing the key interaction with the target protein using a common frame of reference. We have focussed on the status of compounds based on clinical trials in the US and Europe. The data is available in two downloadable forms; a poster format and a double sided desktop version. We hope you find this sheet as useful as we have at UCB.