Major Shareholders

Transparency notification of Vanguard Health Care Fund according to Article 6 of the law of 2 May 2007 on the disclosure of large shareholdings

11 April 2012 – Vanguard Health Care Fund (having its registered offices c/o The Vanguard Group, 455 Devon Park Drive, Wayne, PA 19087 – USA) acquired 5 821 811 UCB shares with voting rights (on a total number of 183 365 052) on 30 March 2012, representing 3.17% of UCB’s share capital, which means that Vanguard Health Care Fund crossed the threshold of notification of 3%.

Transparency notification of Pharmahold SA – Cosylva SA – Compar Finance SA according to Article 6 of the law of 2 May 2007 on the disclosure of large shareholdings

5 April 2012 – Pharmahold SA (having its registered offices at Boulevard du Prince Henri 9b, 1724 Luxemburg), its subsidiary Cosylva SA (having its registered offices at Rue de la Chancellerie 2 bte 1, 1000 Brussels) and Compar Finance SA (having its registered offices at Rue Royale 97, 1000 Brussels), acting in concert, each have sold all their shares, totaling 7 065 830 UCB shares with voting rights on 30 March 2012, which means that Pharmahold SA (taking into account the holding of Cosylva SA) and Compar Finance SA falling jointly below the statutory threshold of 3% for notification.

Transparency notification of Pharmahold SA according to Article 6 of the law of 2 May 2007 on the disclosure of large shareholdings

20 March 2012 – Pharmahold SA (having its registered offices at Boulevard du Prince Henri 9b, 1724 Luxemburg) and its subsidiary Cosylva SA (having its registered offices at Rue de la Chancellerie 2 bte 1, 1000 Brussels) have sold 743 878 UCB shares with voting rights on 15 March 2012, resulting in Pharmahold SA (taking into account the holding of Cosylva SA) falling below the statutory threshold of 3% for notification. Pharmahold SA is currently holding 5 256 122 shares (on a total number of 183 365 052), representing 2.87% of UCB’s share capital.

Various transparency notifications of shareholding according to Article 6 and 14 of the Law of 2 May 2007 on the disclosure of large shareholdings

1 March 2012 - UCB SA/NV received on 1 March 2012 various transparency notifications.

On 28 February 2012, the concerts between Financière de Tubize SA and (i) Degroof Corporate Finance SA, Imofig Sa and Levimmo SA, (ii) Compar Finance SA, (iii) Pharmahold SA and Cosylva SA, respectively, ended.

The concert between Financière de Tubize SA and Schwarz Vermögensverwaltung GmbH & Co KG remains in place (jointly 40.76% of the voting rights).

On 29 February 2012, Pharmahold SA, Cosylva SA and Compar Finance SA entered into a new concert agreement relating to their shares in UCB SA/NV (jointly 4.40% of the voting rights).

An updated chart with the total number of securities and the percentage of voting rights attached thereto is included in the corporate governance charter of UCB SA/NV.

Transparency notification of Wellington Management Company LLP according to Article 14 of the Law of 2 May 2007 on the disclosure of large shareholdings

27 January 2012 - Wellington Management Company, LLP having its registered offices at 75 State Street, Boston, MA 02109, United States of America, sold a number of shares with voting rights on 23 January 2012 crossing down the threshold of 3% of UCB’s capital, the lowest statutory threshold for notification (5 505 950 shares on a total of 183 365 052 or 3%).